animalmodels相关论文
卵巢功能不全（premature ovarian insufficiency，POI）是指女性在40岁前卵巢功能衰退的临床综合征，以月经紊乱（如停经或月经稀发）伴有高促......
Background : Wound healing can result in various outcomes, including hypertrophic scar (HTS). Pigs serve as models to st......
Alzheimer\'s disease and Parkinson\'s disease are two of the most prevalent and disa-bling neurodegenerative disease......
类风湿关节炎(RA)是一种影响多关节的自身免疫性疾病,其特征是关节的进行性炎症和破坏、畸形、活动能力丧失、甚至永久性残疾.尽管......
Autism spectrum disorder (ASD) is typically characterized by common deficits in social skills and repetitive/stereotyped......
At present, treatments for Alzheimer\'s disease can temporarily relieve symptoms but cannot prevent the decline of cog......
During development, regulation of organ size requires a balance between cell proliferation, growth and cell death. Dysre......
Erectile dysfunction is a common side effect of finasteride and dutasteride treatments. The objective of this study was ......
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Influence of chronic extracellular copper deficiency caused by dietary silver ions on the ectopic ce
Copper is an essential trace element for all living organisms.It participates in signaling and is required as catalytic ......
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Detection of intracranial hematoma with different density using Carm Cone-beam Computed Tomography b
Purpose: To evalute the ability of C-arm cone-beam CT to detect intracranial hematomas in canine models. Fourteen health......
Variations in lipoprotein profiles of difference species,analyzed by a fluorescence detection combin
Different animal models have been used to study the pathomechanisms involved in dyslipidemia and evaluate the effect of ......
Nasal Infection of Enterovirus D68 Leading to Lower Respiratory Tract Pathogenesis in Ferrets(Mustel
Data from EV-D68-infected patients demonstrate that pathological changes in the lower respiratory tract are principally ......
Cannabis is an annual flowering herb.It is widely known for its ability in producing cognitive and emotional effects.The......
Echinacea purpurea L.is a medicinal plant originally from North America.It has become a commonly used herbal medicine wo......
Background: Toll-like receptor-7 (TLR7),which recognizes viral single-stranded RNA,can trigger immune complex glomerulon......
This study was designed to investigate the anti-inflammatory effects of volatile oil of Platycladus orientalis(L.)Franco......
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Establishment and pathological study of models of chronic obstructive pulmonary disease by S02 inhal
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A correlative study between AQP4 expression and the manifestation of DWI after the acute ischemic br
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Stroke is a devastating disease with high morbidity and mortality.Animal models are indispensable tools that can mimic s......
An insight on established retinal injury mechanisms and prevalent retinal stem cell activation pathw
Implementing different tools and injury mechanisms in multiple animal models of retina regeneration,researchers have dis......
Heart transplantation is a lifesaving procedure, which is limited by the availability of donor hearts. Using hearts from......
慢传输型便秘动物模型对研究其发病机制和治疗方法具有重要的价值。目前的实验动物以鼠类和犬类为主，构建方法主要是通过药物、物理......
OBJECTIVE: Rat models of hypobaric hypoxia-induced pulmonary hypertension are commonly used in studies of chronic mo......
Parkinsons disease(PD)is a progressive,neurodegenerative disorder of unknown etiology although a complex interaction......
To compare the standard administration protocol to a new administration (1 mg/kg twice a week) to see if dilated car......
目的：观察平脂胶囊对动物血脂和血粘等指标的影响。方法：采用高血脂模型，按照酶学、组织化学及直接测压等方法测定血脂、组织中脂质、......
Taking central nervous system regenerative therapies to the clinic: curing rodents versus nonhuman p
The central nervous system is known to have limited regenerative capacity. Not only does this halt the human body’s rep......
Given the failure to develop disease-modifying therapies for Alzheimer’s disease (AD), strategies aiming at preventing ......
A bright future for the tree shrew in neuroscience research:Summary from the inaugural Tree Shrew Us
Tree shrews(Tupaia spp.)have been used in neuroscience research since the 1960s due to their evolutionary proximity to p......
BACKGROUND: To summarize the metabolic pathway of 1-methyl-4-phenyl-1,2,3,6-tetradropyridine (MPTP)and its mechanism in ......
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The duplication of animal models plays a key role in spinal cord injury research; however, there has been limited study ......
Mesenchymal stem cells require the peripheral immune system for immunomodulating effects in animal m
Multiple sclerosis(MS)is a chronic inflammatory disease of the central nervous system(CNS)that affects oligodendrocytes ......
The interaction of genetics and environmental toxicants in amyotrophic lateral sclerosis: results fr
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in the progres-sive death of......
目的 利用超声造影(CEUS)及定量分析(QLAB)技术对兔单侧输尿管梗阻及不同时间点再通后梗阻侧肾做动态功能研究.方法 实验兔40只随......
动物模型对深入系统研究盆腔炎性疾病（ PID）的发病机制，筛选、开发新药，提高临床疗效具有重要意义。该文对当前PID动物造模方法进行总......
大量流行病学研究表明，高脂血症是动脉粥样硬化等心血管疾病的重要物质基础。构建高脂血症动物模型时，选用合理的高脂配方和合适的动......
多器官功能障碍综合征（ MODS）是当今危重症医学研究的重点，因病死率极高，研究其发病机制是有效治疗的根本，建立可重复性经济标准的动物......
脊髓损伤是一种严重的致残，致死性损伤。其病理生理机制复杂，临床治疗效果不佳。随着脊髓损伤修复机制研究的深入和临床救治水平的提......
丙型肝炎病毒（ HCV）感染是全球关注的公共健康问题之一。只有建立稳定可靠的 HCV感染模型，才能更好地研究HCV感染慢性化和致癌的机制，......
目的观察亚氨基二丙腈(iminodipropionitrile,IDPN)和2,5-二甲氧-4-碘苯-2-氨基丙烷(±-1-2,5-dimethoxy-4-iodophenyl-2-aminopro......
兔颈动脉粥样硬化狭窄模型制备的方法很多,包括内膜空气干燥法、球囊损伤法、颈总动脉套环法、直流电刺激颈动脉外膜法、幽门螺杆......
斑马鱼作为一种新型的脊椎动物模型,目前被广泛应用于骨骼疾病研究,特别是在骨质疏松方面已经取得了较为显著的研究成果.在氟中毒......
目的动态观察Raf-1和ERK在裸鼠移植血管瘤中的表达，探讨其在血管瘤自然退化中的作用。方法动态观察移植瘤大小、形态变化，免疫组织化......
